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KMID : 1145120210190040533
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Asian Journal of Beauty and Cosmetology
2021 Volume.19 No. 4 p.533 ~ p.542
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Effect of Optimal Mixing Ratio of Dendropanax, Sea Salt, and Other Extracts on the Alleviation of Hair Loss Symptoms
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Cho Yeon-Je
Kim Byung-Loc
Han Min-Hee
Lee Hak-Sung
Jeong Yong-Gi
Choi Yun-Hee
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Abstract
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Purpose : This study was conducted to select the optimal mixing ratio (OMR) of extracts including Dendropanax, sea salt, and others from Jeollanam-do and to develop functional cosmetics that can help alleviate hair loss symptoms.
Methods : Our research team determined the OMR through cytotoxicity and cell proliferation tests, and confirmed the anti-inflammatory and anti-microbial effects of the final selected OMR.
Results : The cytotoxicity was low when the OMR was 0.1:1:5:1, but cell proliferation was high, and anti-inflammatory activity effectively inhibited the expression of IL?6 and iNOS. The anti-microbial activity also had an effect on Pseudomonas aeruginosa and Staphylococcus aureus.
Conclusion : This study selected OMR (1:0.1:5:1) to develop functional cosmetics that can help alleviate hair loss symptoms. The final selection of OMR confirmed low cytotoxicity, high cell proliferation, inhibition of expression of IL?6 and iNOS, and anti-microbial activity. Therefore, it is expected to serve as a functional cosmetic that can help alleviate hair loss symptoms in the future.
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KEYWORD
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Optimal mixing ratio, Dendropanax, Sea salt, Hair loss symptoms, Functional cosmetics
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